Dibenamine hydrochloride
CAS No. 55-43-6
Dibenamine hydrochloride ( N-?(2-?Chloroethyl)?dibenzylamine hydrochloride )
Catalog No. M28152 CAS No. 55-43-6
Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDibenamine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionDibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.
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DescriptionDibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.(In Vitro):Dibenamine hydrochloride (100 nM-10 μM) attenuates the extent of cocaine-induced increases in sensitivity to acetylcholine, furthermore, the extent of diphenylamine-induced inhibition depends on the concentration of diphenylamine, which is inversely proportional to the concentration of cocaine. Dibenamine hydrochloride did not have any effect on acetylcholine contraction of isolated guinea-pig vas deferens .(In Vivo):Dibenamine hydrochloride causes a significant increase in the rate of destruction of L-epinephrine in the mouse. Pretreatment with Dibenamine hydrochloride apparently slowed the conversion of Ccl4 to CHCL3. Dibenamine hydrochloride (25 mg/kg; s.c.) decreased the CHCl3, levels at 2 and 6 hr by 30%-50%.
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SynonymsN-?(2-?Chloroethyl)?dibenzylamine hydrochloride
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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RecptorAkt;AP-1;COX;HO-1;MAPK;NF-κB;NO;NOS;Nrf2;p65;PDGFR;PGE;ROS;TNF-α
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Research Area——
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Indication——
Chemical Information
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CAS Number55-43-6
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Formula Weight296.2
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Molecular FormulaC16H19Cl2N
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.ClCCN(Cc1ccccc1)Cc1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wu XD, et al. Bioactive sesquiterpenoids from the flowers of Inula japonica. Phytochemistry. 2016 Sep;129:68-76.
molnova catalog
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